Assoc. Prof. Dr. Pınar Kadiroğulları
Assoc. Prof. Dr. Pınar Kadiroğulları is a specialist in obstetrics and gynecology. She specializes particularly in HPV treatment and cervical cancer prevention, providing holistic healthcare to her patients in the areas of pregnancy monitoring, genital aesthetics, and gynecological surgery.
By combining her academic background with clinical experience, she offers every patient an evidence-based, personalized treatment approach.
Menopause treatment requires a personalized approach to maintain physical and psychological comfort during a crucial period of women’s lives. The average age of menopause in Turkey is 47-49, and women spend approximately one-third of their lives in the postmenopausal period. Therefore, preserving the quality of life is of great importance.
In modern gynecology practice, in accordance with the guidelines of NAMS (North American Menopause Society) and IMS (International Menopause Society); a personalized treatment plan is created considering the patient’s age, severity of symptoms, and accompanying health conditions. Assoc. Prof. Dr. Pınar Kadiroğulları, as an experienced specialist, provides safe guidance during this process, ranging from hormone replacement therapy to holistic supportive approaches at her clinic in Nişantaşı, Istanbul.
Information Note
Menopause is not a disease but a natural biological process. However, the hot flashes, sleep disorders, osteoporosis, and psychological effects of the hormonal changes experienced during this period are treatable. A menopause period with a high quality of life is possible with early intervention. You can also review our Menstrual Irregularity Treatment page →
What Is Menopause?
Menopause is the permanent cessation of the menstrual cycle and the completion of a woman’s reproductive period due to the loss of ovarian activity. Medically, the absence of menstrual bleeding for 12 months is considered sufficient for the diagnosis of menopause. The average age of menopause in Turkey is between 47-49; however, it can vary depending on genetics, lifestyle, and health factors.
During this process, the production of estrogen and progesterone hormones in the ovaries gradually decreases and eventually stops. This change in hormones leads to physiological and psychological symptoms that affect many systems in the body. The primary goals within the scope of menopause treatment are as follows:
1. Symptom Control: Alleviating hot flashes, night sweats, sleep disturbances, and emotional fluctuations.
2. Long-Term Health Preservation: Preventing osteoporosis, cardiovascular diseases, and metabolic problems.
3. Improving Quality of Life: Providing holistic support for sexual health, mental health, and overall comfort of living.
Important Information
Entering menopause before the age of 40 is defined as “early menopause” (premature ovarian insufficiency) and requires special monitoring and treatment. Early menopause can develop due to genetics, autoimmune diseases, chemotherapy/radiotherapy, or following ovarian surgery. In this case, long-term hormone replacement therapy is recommended to reduce the risk of osteoporosis and heart disease.
Menopause Symptoms and Stages
For the success of menopause treatment, it is important to correctly understand the process and know its stages. Menopause is not a single moment but is experienced as a transition process lasting for years and is examined in 3 main stages.
1. Stages of Menopause
- Perimenopause (Transition Period): Begins 4-8 years before menopause. Menstrual irregularities and early symptoms appear.
- Menopause: Diagnosed when 12 months have passed since the last menstrual period. Hormonal changes are most prominent.
- Postmenopause: Covers the entire life period after menopause. Symptoms decrease, but long-term health risks persist.
2. Vasomotor (Temperature) Symptoms
- Hot flashes: The most common symptom, present in 75-80% of women
- Night sweats: Negatively affect sleep quality
- Palpitations: Can be seen due to hormone fluctuations
- Sudden changes in feeling hot and cold
3. Genitourinary (Vaginal/Urinary) Symptoms
- Vaginal dryness and pain during sexual intercourse
- Decrease in sexual desire (loss of libido)
- Increase in urinary tract infections
- Urinary incontinence complaints
4. Psychological and Cognitive Symptoms
- Emotional fluctuations, irritability, and anxiety
- Symptoms of depression
- Sleep disorders and chronic fatigue
- Forgetfulness and difficulty focusing
5. Long-Term Effects
- Osteoporosis: Decrease in bone density and increased risk of fractures
- Cardiovascular diseases: Increased risk of heart and vascular diseases
- Metabolic syndrome and weight gain
- Loss of skin elasticity, hair thinning
Doctor’s Advice
The severity of symptoms varies greatly from person to person. While some women experience mild symptoms, others may encounter severe complaints that seriously affect their daily lives. Individual evaluation and appropriate treatment are critical for a comfortable menopause transition.
Menopause Treatment Options
Menopause treatment is planned with a stepped approach based on the patient’s age, severity of symptoms, accompanying health issues, and personal preferences. The treatment plan is created entirely tailored to the individual, and hormone replacement therapy (HRT) is considered the gold standard in controlling menopausal symptoms.
Step 1 Treatment
Hormone Replacement Therapy (HRT)
- Estrogen + Progesterone Combination: Standard treatment for women with a uterus.
- Estrogen-Only Therapy: Suitable for women who have undergone a hysterectomy.
- Methods of Administration: Oral, transdermal (skin patch), gel, or vaginal form.
- Effect: Reduces hot flashes by 75-90% and vaginal complaints by 80%.
Step 2 Treatment
Hormone-Free Pharmacological Treatments
- SSRI/SNRI Antidepressants: Effective for hot flashes and emotional fluctuations.
- Gabapentin: May be beneficial, especially for night sweats.
- Bisphosphonates: For the prevention and treatment of osteoporosis.
- Vaginal Estrogen Cream: For local vaginal complaints without systemic effects.
Step 3 Treatment
Holistic and Supportive Treatments
- Phytoestrogens: Plant-based estrogen sources such as soy and red clover.
- Calcium + Vitamin D: Essential supplement for bone health.
- Laser Vaginal Regeneration: A modern, non-surgical method for vaginal dryness.
- Multidisciplinary Approach: Support from cardiology, psychiatry, and physiotherapy.
Lifestyle Recommendations and Prevention
Lifestyle adjustments during the menopause treatment process play a critical role in both alleviating current symptoms and protecting against long-term health risks. The following recommendations are evidence-based and supported by NAMS and IMS.
Nutritional Recommendations
- Calcium-rich foods: Dairy products, green leafy vegetables, almonds (1200 mg per day).
- Vitamin D: Fatty fish, eggs, supplements (800-1000 IU per day).
- Phytoestrogens: Soy, flaxseed, and chickpeas help maintain hormonal balance.
- Omega-3 fatty acids: Salmon and walnuts are important for heart health.
- High-fiber foods: Helpful for constipation and weight control.
- Avoid caffeine, alcohol, and spicy foods — these trigger hot flashes.
- Reduce salt consumption — excess salt increases bone loss.
Exercise and Activity
- Regular aerobic exercise: 150 minutes of moderate intensity per week (walking, swimming).
- Resistance exercises: Protects bone density when performed twice a week.
- Yoga and pilates: Provides flexibility, balance, and stress management.
- Adequate sleep: 7-9 hours a day supports hormonal balance.
- Quit smoking — it advances the onset of menopause and increases heart risks.
⚠️ Health Checks Requiring Regular Monitoring
- Annual gynecological examination and smear test
- Mammography: Once a year (for those over 40)
- Bone density (DEXA): For those over 65 or if risk factors are present
- Blood pressure, cholesterol, and blood sugar control
- Cardiovascular health assessment
- Postmenopausal bleeding: Requires urgent evaluation
Important Reminder
Menopause is a new beginning in a woman’s life. With correct medical support and lifestyle adjustments, the postmenopausal period can offer opportunities for a healthy, fulfilling, and active life. What matters is accepting this period, seeking expert support when necessary, and not neglecting regular follow-ups.
Frequently Asked Questions
Is Hormone Replacement Therapy (HRT) Safe?
Hormone replacement therapy is safe and effective with correct patient selection. According to current guidelines, the benefits of HRT far outweigh the risks for healthy women under age 60 or for whom less than 10 years have passed since menopause. In women with a history of breast cancer, past thrombosis, or active heart disease, different treatment options are evaluated. The treatment decision must be made on a personalized basis after an expert evaluation.
Is Weight Gain Inevitable During Menopause?
No, weight gain is not inevitable, but the risk increases. During the menopause period, the slowing of metabolism and hormonal changes can increase the tendency to gain weight. However, a balanced diet, regular exercise, and adequate sleep make weight control possible. Since fat accumulation around the waist increases the risk of metabolic syndrome, particular attention should be paid to abdominal area fat.
How long does hormone replacement therapy (HRT) last?
The duration of HRT is determined on an individual basis. Generally, medical guidelines recommend using the lowest effective dose for the shortest duration necessary to achieve treatment goals. While there is no fixed time limit for everyone, it is standard practice to re-evaluate the treatment plan annually with your specialist to decide whether to continue based on your symptoms and overall health profile.
Does sexual life end during menopause?
Absolutely not; sexual life does not end with menopause. While hormonal changes may lead to vaginal dryness or changes in libido, these issues are treatable with modern medical approaches. With local treatments, hormonal support, and open communication, women can maintain a healthy and satisfying sexual life throughout the postmenopausal years.
What should I do if I am experiencing early menopause?
If you suspect early menopause, the first step is to consult a specialist for a comprehensive hormonal evaluation. Early menopause (before age 40) requires proactive management to protect bone density and cardiovascular health. Your doctor will typically recommend blood tests (FSH, LH, and Estrogen levels) to confirm the diagnosis and may suggest long-term hormone replacement therapy to mitigate the risks associated with early estrogen deficiency until the natural age of menopause.
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References
The medical content on this page has been prepared based on current clinical guidelines and scientific publications from international and national authoritative organizations. In addition to clinical research conducted in Turkey, publications by Assoc. Prof. Dr. Pınar Kadiroğulları in the fields of ovarian function and female endocrinology are included as references.
NAMS 2022 Hormone Therapy Position Statement: The Gold Standard for Menopause Management
Source Author: The North American Menopause Society (NAMS) Advisory Panel | Publication: Menopause 2022;29(7):767-794 | Source Type: Latest International Hormone Therapy Position Statement (PubMed)
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NAMS 2022 Hormone Therapy Position Statement — Full Text PDF
Source Author: The North American Menopause Society (NAMS) | Source Type: Official Full Text PDF (Vasomotor Symptoms, GSM, Bone Loss Prevention)
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NICE NG23: Menopause: Diagnosis and Management — UK National Clinical Guideline
Source Author: National Institute for Health and Care Excellence (NICE) | Publication: NICE Guideline NG23 | Source Type: UK National Clinical Guideline
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The Menopause Experience of Turkish Women: A Qualitative Research
Study: Turkish Academics — semi-structured in-depth interviews | Publication: BMC Women’s Health 2009 | Source Type: First Qualitative Menopause Study in Turkey (PubMed PMC, Full Text)
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Effect of Physical Activity and BMI on Menopausal Symptoms in Turkish Women: A Study of 305 Patients
Authors: Tan MN, Kartal M, Guldal D — Dokuz Eylül University (Izmir) | Publication: BMC Women’s Health 2014 | Study: 305 Turkish women aged 45-60, MRS scores | Source Type: Peer-reviewed Large-scale Turkish Clinical Study (PubMed PMC, Full Text)
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Menopausal Status and Attitudes in a Population of Middle-Aged Turkish Women: A Large-Scale Epidemiological Study
Study: 1,551 women, multi-stage sampling, Western Turkey | Publication: BMC Women’s Health 2010 | Source Type: Large-scale Peer-reviewed Turkish Clinical Study (Full Text)
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IMS Recommendations: Risk-Benefit Profile in Postmenopausal Hormone Therapy — International Consensus
Source Author: International Menopause Society (IMS) | Publication: Climacteric 2016 | Source Type: International Menopause Consensus Report (PubMed)
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Assoc. Prof. Dr. Pınar Kadiroğulları’s Publications on Ovarian Function and Female Endocrinology
The decline of ovarian function lies at the foundation of menopause pathophysiology — scientific publications by the doctor on this subject
Relationship Between HbA1c Levels and Ovarian Reserve: A Study in Female Endocrinology
Authors: Kadiroğulları P, Demir E, Bahat PY, Kıyak H, Seçkin KD | Publication: Gynecological Endocrinology 2020;36(5):426-430 | Source Type: International Peer-reviewed Scientific Article (PubMed)
This publication directly addresses clinical indicators of ovarian reserve (egg count/quality) — it is a significant reference as the decline in ovarian reserve is the fundamental mechanism in menopause pathophysiology.
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Modified Extraperitoneal Uterosacral Ligament Suspension: A Vaginal Surgical Technique for Postmenopausal Pelvic Organ Prolapse
Authors: Kadiroğulları P, Seçkin KD | Publication: Journal of Investigative Surgery 2019 | Source Type: Peer-reviewed Clinical Research (PubMed)
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Effect of Dydrogesterone (Progesterone) Use on Female Sexual Function
Authors: Yalçın Bahat P, Yücel B, Yuksel Özgör B, Kadiroğulları P, Topbas Selçuki NF, Çakmak K | Publication: Journal of Obstetrics and Gynaecology 2022;42(5):1276-1279 | Source Type: Peer-reviewed Hormone Therapy Study (PubMed)
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Important Note
The information on this page is for general informational purposes and does not substitute for individual medical advice. For diagnosis of menopause, evaluation for hormone replacement therapy (HRT), and personal health questions, please consult your specialist gynecologist. The page content has been prepared by Assoc. Prof. Dr. Pınar Kadiroğulları in the light of clinical experience and current scientific literature.
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