Assoc. Prof. Dr. Pınar Kadiroğulları
Assoc. Prof. Dr. Pınar Kadiroğulları is a specialist in obstetrics and gynecology. She works in the areas of pregnancy monitoring, HPV and cervical health, genital aesthetics, and gynecological surgery.
Her approach is based on current scientific guidelines.
G-Shot and O-Shot are injection procedures whose use in female sexual health is under investigation. These procedures do not require a surgical incision and are performed in an outpatient setting; however, scientific data on their effectiveness and long-term safety are limited.
The patient’s complaints, expectations, and sexual function status are evaluated by examination, and the decision is made according to this evaluation. This page summarizes what the procedures are, in which complaints they may be considered, and the limits of the scientific data.
Information Note
G-Shot and O-Shot are procedures that do not require a surgical incision. The duration varies depending on the procedure; most people can return to daily life the same day. There is no definite information on when the effect begins or how long it lasts; results vary from person to person. For surgical options, you can visit our Vaginoplasty and Hoodoplasty pages.
What Are G-Shot and O-Shot?
G-Shot and O-Shot are two different injection methods whose use in female sexual health is under investigation. Both procedures aim to support sexual function without surgery. The choice of which method to apply is determined based on the patient’s complaints, expectations, and clinical evaluation.
What Is the G-Shot?
The G-Shot (Grafenberg Shot) is a procedure in which hyaluronic acid (HA) is injected into the G-spot located on the anterior wall of the vagina. The G-spot is the projection of the internal extension of the clitoris on the anterior vaginal wall and is known in some women as the “deep orgasm” point. It is claimed that HA injection increases the sensitivity of this area; however, controlled studies showing this effect are limited.
What Is the O-Shot?
The O-Shot (Orgasm Shot) is an injection of PRP (Platelet Rich Plasma) obtained from the patient’s own blood. It is injected into the clitoral area and the vagina. The growth factors in PRP are thought to support tissue repair. Its effect on sexual arousal, lubrication, and orgasm has not yet been definitively proven.
Differences Between the Two Methods
- G-Shot: Hyaluronic acid (HA) — a filler material
- O-Shot: PRP — obtained from the patient’s own blood
- G-Shot: A volume effect is targeted
- O-Shot: A contribution to tissue repair is targeted
- Both methods can be combined in the same session
Important Information
G-Shot and O-Shot do not require a surgical incision. They are performed after a local anesthetic cream is applied; the duration varies depending on the procedure. Most people can return to daily life the same day. The period of abstinence from sexual intercourse is determined by the physician (usually 24-48 hours).
In Which Cases Are G-Shot and O-Shot Performed?
G-Shot and O-Shot treatments are planned according to the patient’s clinical complaints and expectations. These procedures may be considered in people presenting with the following complaints. Standard treatments with proven benefit (e.g., local hormone therapy, pelvic floor exercises, sexual therapy) are evaluated first.
1. Sexual Health Issues
- Difficulty with sexual arousal and decreased sensitivity
- Difficulty achieving orgasm (anorgasmia) or inability to reach orgasm
- Decreased sexual pleasure and reduced satisfaction
- Vaginal dryness and insufficient lubrication
- Pain during sexual intercourse (dyspareunia)
- Decreased sexual desire (hypoactive sexual desire)
- Decreased clitoral sensitivity
2. Conditions Related to Age and Hormonal Changes
- Sexual problems during and after the menopausal period. For details, you can visit our Menopause Treatment page.
- Perimenopausal changes
- Vaginal atrophy due to estrogen deficiency
- Age-related loss of vaginal tissue elasticity
- Postpartum temporary sexual issues
3. Urinary System Issues (Particularly O-Shot)
- Mild urinary incontinence (stress incontinence). For details, you can visit our Urinary Incontinence Treatment page.
4. Other Concurrent Procedures
- Supportive treatment after vaginoplasty
- Complementary treatment after hoodoplasty
- Postpartum sexual rehabilitation
Diagnosis and Evaluation
The decision for G-Shot and O-Shot is made through a detailed examination. The patient’s sexual history, hormonal status, and any accompanying pathologies are evaluated. The treatments are not applied in cases of pregnancy, active infection, or bleeding disorders. The timing of the procedure is planned by the physician.
G-Shot and O-Shot Application Methods
G-Shot and O-Shot treatments are planned by considering the patient’s complaints, expectations, and clinical condition. The procedures described are G-Shot (HA), O-Shot (PRP), and a combined application performed in the same session. The superiority of any one over the others has not been demonstrated scientifically.
Method 1
G-Shot (Hyaluronic Acid)
A treatment in which the G-spot on the anterior wall of the vagina is enhanced through a hyaluronic acid (HA) injection.
- Indications: Difficulty with sexual arousal and difficulty achieving orgasm.
- Duration: 15-20 minutes, with a topical anesthetic cream.
- Feature: A volume effect is targeted; HA is gradually broken down by the body.
Method 2
O-Shot (PRP Application)
A treatment in which PRP (Platelet Rich Plasma) obtained from the patient’s own blood is injected into the clitoral and vaginal areas.
- Indications: Vaginal atrophy, dryness, and urinary incontinence.
- Duration: 30-45 minutes (blood draw + procedure).
- Feature: Prepared from the patient’s own blood; a foreign-substance allergy is not expected, but there is a risk of injection-related infection, bruising, and bleeding.
Method 3
Combined Application (G-Shot + O-Shot)
Both procedures are applied together in the same session. There is insufficient data showing that combined application is more effective than either alone.
- Considered in: Cases with more than one sexual function complaint.
- Duration: The duration of the blood draw and the two procedures varies depending on the procedure.
Duration of Effects and Results After G-Shot and O-Shot
After G-Shot and O-Shot procedures, most people can return to daily life the same day. Outcomes vary from person to person.
Post-Treatment Period
- First 24 hours: Mild swelling or redness (normal)
- Sexual intercourse: Can be resumed after 24-48 hours
- Bathing: Standing showers can be taken the same day
- Sports: Can be resumed after 48-72 hours
- Tampon use: Should be avoided for 48 hours
- Normal life: Same-day return is possible
Duration of Effects
⚠️ When to Consult a Physician
- Fever above 38°C or chills
- Excessive swelling or increasing bruising
- Severe and persistent pain
- Excessive vaginal bleeding
- Redness, discharge, or foul odor at the injection site
- Signs of an allergic reaction (itching, rash)
Important Reminder
The scientific data on G-Shot and O-Shot are limited, and results vary from person to person. Whether they are suitable for you can be discussed with your doctor.
Frequently Asked Questions
Are G-Shot and O-Shot painful?
Before the procedure, a topical anesthetic cream is applied and given sufficient time to take effect. Mild pressure or discomfort may be felt during the injection; the blood draw for the O-Shot causes additional discomfort. Some patients may experience mild tenderness for 1-2 days after the procedure; this is normal and can easily be managed with painkillers.
How long do the effects of G-Shot and O-Shot last?
There is no definite information on how long the effects last, and the duration varies from person to person. Individual differences (age, hormonal status, lifestyle) may influence the duration of effect.
Is the PRP used in O-Shot treatment safe?
PRP is obtained from the patient’s own blood. As with any injection, there is a risk of infection, bruising, and bleeding. After the blood is drawn, it is processed in a specialized centrifuge device, the platelet-rich portion is separated, and it is injected during the same session. Its use in the genital area is at the research stage.
Who Should Not Receive G-Shot and O-Shot?
G-Shot and O-Shot are not applied in certain conditions. The contraindications include: pregnancy, breastfeeding, active vaginal infection, bleeding disorders, the use of blood-thinning medications, active cancer treatment, and autoimmune diseases. Additionally, the G-Shot is not recommended for those with a hyaluronic acid allergy, and the O-Shot is not recommended for those with a platelet function disorder. Suitability for the procedure is determined through a detailed examination.
Can G-Shot and O-Shot Be Combined with Other Treatments?
G-Shot and O-Shot can be performed in the same session; there is insufficient data showing that combined treatments are more effective than a single procedure. The most appropriate combination is determined by the doctor following a clinical evaluation of the patient.
Our Treatments
References
The medical content on this page has been prepared based on the current clinical guidelines and scientific publications of national and international authoritative organizations. Below, you can review the main PDF references — including those from Turkish gynecology journals — and the academic publications of Assoc. Prof. Dr. Pınar Kadiroğulları.
The Effect of PRP Application to the Lower Anterior Vaginal Wall on Female Sexual Satisfaction
Authors: Sukgen G, Ellibeş Kaya A, Karagün E, Çalışkan E | Publication: Turk J Obstet Gynecol (Journal of the Turkish Society of Obstetrics and Gynecology) 2019;16:228-234 | Source Type: Turkish Peer-Reviewed Clinical Study (PubMed PMC, Full Text)
Evaluation of the Efficacy of Injectable PRF in Genitourinary Syndrome of Menopause
Publication: Journal of the Turkish-German Gynecological Association 2024 | Source Type: Turkish Peer-Reviewed Clinical Research
The Relationship Between Women’s Self-Reported G-Spot Existence and Sexual Function and Genital Perception
Authors: Kaya AE, Çalışkan E | Publication: Turk J Obstet Gynecol 2018;15:182-187 | Source Type: Turkish Peer-Reviewed Clinical Study
Elective Female Genital Cosmetic Surgery — Committee Opinion No. 795
Author: American College of Obstetricians and Gynecologists (ACOG) | Publication: Obstet Gynecol 2020 | Source Type: Committee Opinion / Standards in Aesthetic Gynecology
G-spot: Fact or Fiction? A Systematic Review
Publication: Sexual Medicine Reviews 2021 (International Society for Sexual Medicine – ISSM) | Source Type: Peer-Reviewed Systematic Review (PubMed PMC)
The Efficacy and Safety of PRP Injections in Female Sexual Dysfunction and Stress Urinary Incontinence: A Systematic Review
Publication: Journal of Personalized Medicine 2023 | Source Type: Peer-Reviewed Systematic Review (PubMed PMC, Full Text)
ICS/ISSVD Best Practice Consensus: Clinical Vulvar and Vaginal Laser Applications
Authors: Preti M, Vieira-Baptista P, Digesu GA, et al. (ICS/ISSVD Joint Working Group) | Publication: Neurourol Urodyn 2019 | Source Type: International Consensus Document
📚 Selected Academic Publications by Assoc. Prof. Dr. Pınar Kadiroğulları
The Effect of Dydrogesterone Treatment on Sexual Function (FSFI) in Women with Endometriosis
Authors: Yalçın Bahat P, Yücel B, Yuksel Özgör B, Kadiroğulları P, Topbas Selçuki NF, Çakmak K | Publication: Journal of Obstetrics and Gynaecology 2022;42(5):1276-1279 | Source Type: Peer-Reviewed Clinical Research (PubMed)
Clitoral Hoodoplasty Techniques: Patient Selection, Indications, and the Impact on Sexual Function
Authors: Bozkurt Köseoğlu S, Çalışkan E, Kadiroğulları P | Publication: Anatolian Journal of Obstetrics and Gynecology Research 2024 | Source Type: Turkish Peer-Reviewed Review
Modified Extraperitoneal Uterosacral Ligament Suspension: Preventing Vaginal Cuff Prolapse After Vaginal Hysterectomy — A 4-Clamp Technique
Authors: Kadiroğulları P, Seçkin KD | Publication: Journal of Investigative Surgery 2019 | Source Type: Peer-Reviewed Clinical Research (PubMed)
Important Note
The information on this page is intended for general informational purposes and does not replace individual medical advice. For personal questions regarding G-Shot, O-Shot, and sexual pleasure enhancement treatments, you should always consult your specialist gynecologist. The content of this page has been prepared by Assoc. Prof. Dr. Pınar Kadiroğulları in light of clinical experience and current scientific literature.
“Obstetrics and Gynecology”
